Toxicology Litigation Support
The Ephedra alkaloids are based on a chemical class of enantiomers which are structurally similar to amphetamines and metamphetamines. As such, they act in a similar way on adrenergic receptors and, not surprisingly, they are thought to be addictive. Nutritional supplements and cold remedies containing Ephedra alkaloids are thought to cause peak elevations in blood pressure and hemorrhagic strokes in susceptible individuals. Dr. Parent has written an expert report on the causal relationship between the use of Ephedra alkaloids and hemorrhagic stroke in which he employs the Hill Criteria to meet the requirements of Daubert. A report and selected references are provided below.
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Theoharides, T. C., Sudden death of a healthy college student related to ephedrine toxicity from a ma huang-containing drink. Journal of Clinical Psychopharmacology, 17(5), 437-439 (1997).
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